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4-Hydroxy-3-methoxymandelic acid

CAS No. 55-10-7

4-Hydroxy-3-methoxymandelic acid( —— )

Catalog No. M14995 CAS No. 55-10-7

Vanillyl mandelic acid (VMA) is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 35 In Stock
50MG 50 In Stock
100MG 72 In Stock
200MG 106 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    4-Hydroxy-3-methoxymandelic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Vanillyl mandelic acid (VMA) is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine.
  • Description
    Vanillyl mandelic acid (VMA) is a chemical intermediate in the synthesis of artificial vanilla flavorings and is an end-stage metabolite of the catecholamines, epinephrine, and norepinephrine. It is produced via intermediary metabolites.
  • In Vitro
    Vanillylmandelic acid has antioxidant activity, the IC50 value is determined as the amount of VMA required to reduce 50% of the starting concentration of free radical is 33*10-6 M in the UV-Vis decolourisation DPPH assay.
  • In Vivo
    Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    55-10-7
  • Formula Weight
    198.17
  • Molecular Formula
    C9H10O5
  • Purity
    >98% (HPLC)
  • Solubility
    Limited solubility
  • SMILES
    COC1=C(O)C=CC(=C1)C(O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kolentinis MK, et al. Eur J Pharmacol. 2013 Mar 5;703(1-3):46-52.
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